Gastrointestinal stromal tumors: risk assessment and adjuvant therapy.

@article{Joensuu2013GastrointestinalST,
  title={Gastrointestinal stromal tumors: risk assessment and adjuvant therapy.},
  author={Heikki Joensuu},
  journal={Hematology/oncology clinics of North America},
  year={2013},
  volume={27 5},
  pages={889-904}
}
Adjuvant imatinib prolongs recurrence-free survival and probably overall survival of patients who have undergone surgery for gastrointestinal stromal tumor (GIST). Estimation of the risk of recurrence with a prognostication tool and tumor mutation analysis is essential before imatinib initiation, because approximately 60% of patients with GIST with operable tumor are cured by surgery alone and some mutated tyrosine kinases are insensitive to imatinib. Adjuvant imatinib is usually administered… CONTINUE READING

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