Gastrointestinal mucosal injury in experimental models of shock, trauma, and sepsis.

@article{Fink1991GastrointestinalMI,
  title={Gastrointestinal mucosal injury in experimental models of shock, trauma, and sepsis.},
  author={Mitchell P. Fink},
  journal={Critical care medicine},
  year={1991},
  volume={19 5},
  pages={627-41}
}
BACKGROUND AND METHODS The mucosa of the GI tract serves as an important barrier limiting the systemic absorption of luminal microbes and microbial products. Two methods commonly used to assess the integrity of the GI mucosal barrier are assessment of the extent of microbial translocation and measurement of mucosal permeability to hydrophilic probes. RESULTS Studies using these methods have provided convincing evidence that the barrier function of the intestinal mucosa is deranged in numerous… CONTINUE READING
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