Gastrointestinal motility disorders in scleroderma.

  title={Gastrointestinal motility disorders in scleroderma.},
  author={Robert Sjogren},
  journal={Arthritis and rheumatism},
  volume={37 9},
After the skin, the gastrointestinal tract is the second most common target of systemic sclerosis. The major clinical manifestations include gastroesophageal reflux, small bowel bacterial overgrowth, malnutrition, and intestinal pseudoobstruction. Treatment is symptomatic and supportive. Gastroesophageal reflux can usually be adequately managed with prokinetic drugs, omeprazole, and judicious use of antireflux surgery. If Barrett's esophagus is present, periodic endoscopic monitoring for… CONTINUE READING


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