Gastrointestinal inflammation and associated immune activation in schizophrenia.

  title={Gastrointestinal inflammation and associated immune activation in schizophrenia.},
  author={E Severance and Armin Alaedini and Shuojia Yang and Meredith L Halling and Kristin L. Gressitt and Cassie R. Stallings and Andrea E. Origoni and Crystal Vaughan and Sunil Khushalani and F. Markus Leweke and Faith Dickerson and Robert Yolken},
  journal={Schizophrenia research},
  volume={138 1},
Immune factors are implicated in normal brain development and in brain disorder pathogenesis. Pathogen infection and food antigen penetration across gastrointestinal barriers are means by which environmental factors might affect immune-related neurodevelopment. Here, we test if gastrointestinal inflammation is associated with schizophrenia and therefore, might contribute to bloodstream entry of potentially neurotropic milk and gluten exorphins and/or immune activation by food antigens. IgG… CONTINUE READING
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