Gastrointestinal health care resource utilization with chronic use of COX-2-specific inhibitors versus traditional NSAIDs.

@article{Laine2003GastrointestinalHC,
  title={Gastrointestinal health care resource utilization with chronic use of COX-2-specific inhibitors versus traditional NSAIDs.},
  author={L Laine and J. A. Cima andW. R. Wogen and Holly Yu},
  journal={Gastroenterology},
  year={2003},
  volume={125 2},
  pages={389-95}
}
BACKGROUND & AIMS Cyclooxygenase 2 (COX-2)-specific inhibitors (coxibs) decrease gastrointestinal (GI) events in controlled trials, but results in clinical practice are unknown. We assessed GI-related resource use and costs in patients switching from chronic nonsteroidal anti-inflammatory drug (NSAID) therapy to chronic coxib therapy and in patients starting chronic NSAID therapy vs. chronic coxib therapy in a U.S. administrative claims database of >8 million lives. METHODS "Switchers" (n… CONTINUE READING
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