Gastrointestinal growth factors and neoplasia.

  title={Gastrointestinal growth factors and neoplasia.},
  author={Bernard Mark Evers},
  journal={American journal of surgery},
  volume={190 2},
Gastrointestinal (GI) hormones are chemical messengers that have been recognized for over a century as regulatory factors for normal physiologic functions in the GI tract and pancreas, including absorption, secretion, motility, and digestion. These hormones traditionally act in a true endocrine fashion with release from a distant site to regulate physiologic functions of specific target organs. In general, GI hormones bind to their G-protein-coupled receptors (GPCRs) to produce their endocrine… CONTINUE READING