Gastrointestinal dysfunction in Parkinson's disease: frequency and pathophysiology.

  title={Gastrointestinal dysfunction in Parkinson's disease: frequency and pathophysiology.},
  author={Louis L. Edwards and Eamon M Quigley and Ronald F. Pfeiffer},
  volume={42 4},
Although more extensive research is required to fully characterize the pathophysiology of the gastrointestinal symptoms in PD, much of the presently available data suggest that the primary PD process is the major factor in the etiology of gut dysfunction in this patient population. This may be mediated by both central and peripheral mechanisms. Involvement of the dorsal motor nucleus of the vagus might produce dysfunction of muscles controlling deglutition and esophageal motility, thereby… CONTINUE READING
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