Gastrointestinal Tract Antigenic Profile of Cotton-Top Tamarin, Saguinus oedipus, is Similar to That of Humans with Inflammatory Bowel Disease

As an animal model for human inflammatory bowel disease and colorectal cancer, the cotton-top tamarin remains controversial. Demonstration of antigenic similarity to the human would enhance its validity. Using colonic extracts and washings, we compared binding of seven monoclonal antibodies reactive with bowel and cancer antigens in both tamarins and humans… CONTINUE READING