Gastrointestinal Diagnosis of Classical Whipple Disease: Clinical, Endoscopic, and Histopathologic Features in 191 Patients

@inproceedings{Gnther2015GastrointestinalDO,
  title={Gastrointestinal Diagnosis of Classical Whipple Disease: Clinical, Endoscopic, and Histopathologic Features in 191 Patients},
  author={Ute G{\"u}nther and Verena Moos and Gabriel Offenm{\"u}ller and Gerrit Oelkers and Walther Heise and Annette Moter and Christoph Loddenkemper and Thomas Schneider and Carlo Maria Girelli.},
  booktitle={Medicine},
  year={2015}
}
Classic Whipple disease (CWD) is a systemic infection caused by Tropheryma whipplei. Different diagnostic tools have been developed over the last decades: periodic acid-Schiff (PAS) staining, T whipplei-specific polymerase chain reaction (PCR), and T whipplei-specific immunohistochemistry (IHC). Despite all these advances, CWD is still difficult to diagnose because of a variety of clinical symptoms and possibly a long time span between first unspecific symptoms and the full-blown clinical… CONTINUE READING