Gastroesophageal reflux in laryngopharyngeal reflux patients: Clinical features and therapeutic response

@article{Lechien2019GastroesophagealRI,
  title={Gastroesophageal reflux in laryngopharyngeal reflux patients: Clinical features and therapeutic response},
  author={J{\'e}r{\^o}me Ren{\'e} Lechien and François Bobin and Vinciane Muls and Pierre Eisendrath and Mihaela Horoi and Marie Paule Thill and Didier Dequanter and Jean-Pierre Durdurez and Alexandra Rodr{\'i}guez and Sven Saussez},
  journal={The Laryngoscope},
  year={2019},
  volume={130}
}
To investigate the clinical features and the therapeutic response of laryngopharyngeal reflux (LPR) patients with or without gastroesophageal reflux disease (GERD). 
Management of Laryngopharyngeal Reflux Around the World: An International Study
To investigate worldwide practices of otolaryngologists in the management of laryngopharyngeal reflux (LPR).
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Hypopharyngeal‐Esophageal Impedance‐pH Monitoring Profiles of Laryngopharyngeal Reflux Patients
TLDR
To investigate the profile of patients with LPR at hypopharyngeal–esophageal multichannel intraluminal impedance‐pH (HEMII‐ pH) monitoring and the relationship between hypopharygeal‐proximal reflux episodes (HREs) and saliva pepsin concentration, a novel approach is proposed. Expand
Laryngopharyngeal Reflux Disease is More Severe in Obese Patients: A Prospective Multicenter Study.
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Laryngopharyngeal Reflux in Hypertrophic Laryngeal Diseases.
TLDR
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Association Between Laryngopharyngeal Reflux and Media Otitis: A Systematic Review
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  • Medicine
  • Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • 2021
TLDR
The association between LPR and OM is still unclear and future clinical and experimental studies are needed through extensive gastric content analysis in middle ear suppurations and impedance-pH monitoring considering acid, weakly acid, and alkaline reflux events. Expand
Distinct Clinical Physiologic Phenotypes of Patients with Laryngeal Symptoms Referred for Reflux Evaluation.
  • R. Yadlapati, A. Kaizer, +11 authors W. Chan
  • Medicine
  • Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2021
TLDR
Phenotypic differences may inform targeted clinical trials design and improve outcomes and identify distinct clinico-physiologic phenotypes of patients with laryngeal symptoms referred for reflux evaluation. Expand
Laryngopharyngeal Reflux: A State-of-the-Art Algorithm Management for Primary Care Physicians
TLDR
A practical algorithm for LPR management for GPs and other specialists that cannot perform fiberoptic examination is provided and physicians have to exclude some confounding conditions such as allergy or other causes of pharyngolaryngitis and “red flags”. Expand
Laryngopharyngeal Reflux and Inflammatory Responses in Mucosal Barrier Dysfunction of the Upper Aerodigestive Tract
TLDR
This review describes the components and functions of the mucosal barrier and the results of LPR-induced mucosal inflammation in the UAT and discusses the dynamic alterations in the mucosa barrier that might be potential therapeutic targets for L PR-induced disorders. Expand
Study on laryngopharyngeal and esophageal reflux characteristics using 24-h multichannel intraluminal impedance-pH monitoring in healthy volunteers
TLDR
Non-acid reflux in the upright position is characteristic of laryngopharyngealReflux disease and the diagnostic indicators of gastroesophageal reflux disease are not suitable for larygopharynx and esophagus in asymptomatic volunteers. Expand
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TLDR
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