Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study

@inproceedings{Egloff2012GastrinreleasingPR,
  title={Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study},
  author={Ann Marie Egloff and Autumn L Gaither Davis and Yongli Shuai and Stephanie R. Land and Joseph Pilewski and James D. Luketich and Rodney J. Landreneau and York E. Miller and Jennifer R Grandis and Jill M. Siegfried},
  booktitle={Respiratory research},
  year={2012}
}
BACKGROUND Normal bronchial tissue expression of GRPR, which encodes the gastrin-releasing peptide receptor, has been previously reported by us to be associated with lung cancer risk in 78 subjects, especially in females. We sought to define the contribution of GRPR expression in bronchial epithelia to lung cancer risk in a larger case-control study where adjustments could be made for tobacco exposure and sex. METHODS We evaluated GRPR mRNA levels in histologically normal bronchial epithelial… CONTINUE READING
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