Gastrin-releasing peptide and cancer.

@article{Patel2006GastrinreleasingPA,
  title={Gastrin-releasing peptide and cancer.},
  author={Oneel Patel and Arthur Shulkes and Graham S Baldwin},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1766 1},
  pages={23-41}
}
Over the past 20 years, abundant evidence has been collected to suggest that gastrin-releasing peptide (GRP) and its receptors play an important role in the development of a variety of cancers. In fact, the detection of GRP and the GRP receptor in small cell lung carcinoma (SCLC), and the demonstration that anti-GRP antibodies inhibited proliferation in SCLC cell lines, established GRP as the prototypical autocrine growth factor. All forms of GRP are generated by processing of a 125-amino acid… CONTINUE READING
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