Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK2 receptor.

Abstract

BACKGROUND AND AIMS Factors associated with the development and malignant progression of Barrett's esophagus are poorly understood. Gastrin is a mitogen capable of inducing growth in normal and malignant gastrointestinal mucosa. It is unknown whether gastrin can influence cellular events in the esophagus in Barrett's. METHODS Reverse-transcription… (More)

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@article{Haigh2003GastrinIP, title={Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK2 receptor.}, author={Chris R Haigh and Stephen Edwin Arthur Attwood and David G. Thompson and Janusz A. Z. Jankowski and Chris M Kirton and D Mark Pritchard and Andrea Varr{\'o} and Rod Dimaline}, journal={Gastroenterology}, year={2003}, volume={124 3}, pages={615-25} }