Gastrin induces expression and promoter activity of the vesicular monoamine transporter subtype 2.

@article{Gerhard2001GastrinIE,
  title={Gastrin induces expression and promoter activity of the vesicular monoamine transporter subtype 2.},
  author={Markus Gerhard and Nina Neumayer and E Presecan-Siedel and Robert Zanner and Ernst Lengyel and Torsten Cramer and Michael Hoecker and Christian Prinz},
  journal={Endocrinology},
  year={2001},
  volume={142 8},
  pages={3663-72}
}
Gastric enterochromaffin-like cells produce histamine in response to the antral hormone gastrin and accumulate the biogenic amine in secretory organelles via vesicular monoamine transporter subtype 2. The putative effects of gastrin on vesicular monoamine transporter subtype 2 expression and promoter activity are poorly understood. In the present study we used highly enriched rat enterochromaffin-like cells (purity, >90%) and rat pheochromocytoma cells stably transfected with a gastrin… CONTINUE READING