Gastric retention properties of superporous hydrogel composites.

  title={Gastric retention properties of superporous hydrogel composites.},
  author={J.-S. Chen and William E. Blevins and Hungkyu Park and Kuyson Park},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  volume={64 1-3},
In many applications, usefulness of conventional hydrogels is limited by their slow swelling. To improve the swelling property of the conventional hydrogels, we have synthesized superporous hydrogels (SPHs) which swell fast to equilibrium size in minutes due to water uptake by capillary wetting through numerous interconnected open pores. The swelling ratio was also large in the range of hundreds. The mechanical strength of the highly swollen SPHs was increased by adding a composite material… CONTINUE READING

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