Gastric or Rectal Instillation of Short-Chain Fatty Acids Stimulates Epithelial Cell Proliferation of Small and Large Intestine in Rats

Abstract

Short-chain fatty acids stimulate gut epithelial cell proliferation in vivo, although the difference between oral and rectal routes is unknown. Accordingly, we examined the effect of oral or rectal administration of these acids. We instilled a mixture of acetic acid, propionic acid, and n-butyric acid (150, 60, and 60 mmol/liter, respectively; pH 6.5) or… (More)
DOI: 10.1023/A:1015014829605

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