Gastric mucus of the guinea pig: proton carrier and diffusion barrier.

@article{Schreiber1997GastricMO,
  title={Gastric mucus of the guinea pig: proton carrier and diffusion barrier.},
  author={Soeren Schreiber and Peter Scheid},
  journal={The American journal of physiology},
  year={1997},
  volume={272 1 Pt 1},
  pages={G63-70}
}
Proton transport with the gastric mucus was investigated in the guinea pig in vitro by use of three experimental series. In series I, pH profiles were obtained in the mucus and mucosa of a gastric explant with fine-tipped double-barreled microelectrodes. With a luminal pH of 1.8, pH increased across this layer to approximately 6 at the epithelial surface. Thickness of the gastric mucous gel layer increased continuously by 170 +/- 100 microns/h in the unstimulated and by 450 +/- 120 microns/h in… CONTINUE READING

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