Gastric mucosal cytokine and epithelial cell responses to Helicobacter pylori infection in Mongolian gerbils.

@article{Crabtree2004GastricMC,
  title={Gastric mucosal cytokine and epithelial cell responses to Helicobacter pylori infection in Mongolian gerbils.},
  author={Jean E. Crabtree and Michelle Court and Mohamed A Aboshkiwa and Anthony H.T. Jeremy and Michael F. Dixon and Philip A. Robinson},
  journal={The Journal of pathology},
  year={2004},
  volume={202 2},
  pages={197-207}
}
Experimental infection with Helicobacter pylori in Mongolian gerbils results in chronic gastritis and gastric cancer. To investigate epithelial cell proliferation, apoptosis, and mucosal cytokine responses in gastritis, Mongolian gerbils were infected with the H pylori SS1 strain. At 4 weeks post-infection, gastritis was predominantly within the antrum, but extended to the corpus in approximately 50% of gerbils by 36 weeks. Epithelial cell proliferation and apoptosis in glandular epithelial… CONTINUE READING