Gastric metastases from testicular cancer: case report and review of literature.


Testicular germ cell tumors represent approximately 1 % of all cancers in man and are the most common malignancy between 15and 35-year olds [1, 2]. Testicular malignancy has a common precursor and reflects a continuum of differentiation potential of early neoplastic germ cell. They are classified into seminomas (classic and spermatocytic) and non-seminomas (embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma). Seminomas are characterized by a more favorable clinical outcome compared to nonseminomas [3]. Pure seminomatous cancers account for 40 % of cases, while non-seminomatous and mixed tumors represent about 60 % of cases [1]. Approximately one half of patients with non-seminomatous germ cell tumors present at stage IV [2, 4]. Generally, these tumors metastasize to the retroperitoneal lymph nodes and, less commonly, to the lungs, liver, and brain [5]. Gastrointestinal metastases are very rare and may present with bowel obstruction or, less frequently, with hemorrhage [6]. We present the case of a 44-year-old man affected by a mixed testicular cancer, who began with symptoms related to bleeding from gastric metastasis.

DOI: 10.1007/s12029-013-9524-4

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@article{Lauro2014GastricMF, title={Gastric metastases from testicular cancer: case report and review of literature.}, author={Salvatore Di Lauro and Riccardo Righini and Concetta Elisa Onesti and Eugenio Pucci and Alessandra Bramini and Paolo Marchetti}, journal={Journal of gastrointestinal cancer}, year={2014}, volume={45 Suppl 1}, pages={22-4} }