Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients

@article{Gutierrez1992GastricIP,
  title={Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients},
  author={Guillermo Gutierrez and Fernando P{\'a}lizas and Guillermo Raul Doglio and J. F. Pusajo and Rodolfo Giniger},
  journal={The Lancet},
  year={1992},
  volume={339},
  pages={195-199}
}
Falls in gastric intramucosal pH (pHi) are associated with morbidity and mortality in patients admitted to intensive-care units (ICU). We tested the hypothesis that ICU outcome can be improved by therapy guided by changes in pHi and aimed at improving systemic oxygen availability. We studied 260 patients admitted to ICUs with APACHE II scores of 15-25. After insertion of a gastric tonometer, each patient was randomly assigned to a control or protocol group within the admission pHi category… CONTINUE READING

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