Gastric emptying of hexose sugars: role of osmolality, molecular structure and the CCK₁ receptor.

@article{Little2010GastricEO,
  title={Gastric emptying of hexose sugars: role of osmolality, molecular structure and the CCK₁ receptor.},
  author={Tanya J. Little and Aathira Gopinath and Ebrahim Patel and Andrew McGlone and Daniel J Lassman and Mauro D'Amato and John T. McLaughlin and David G. Thompson},
  journal={Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society},
  year={2010},
  volume={22 11},
  pages={1183-90, e314}
}
BACKGROUND It is widely reported that hexose sugars slow gastric emptying (GE) via osmoreceptor stimulation but this remains uncertain. We evaluated the effects of a panel of hexoses of differing molecular structure, assessing the effects of osmolality, intra-individual reproducibility and the role of the CCK(1) receptor, in the regulation of GE by hexoses. METHODS Thirty one healthy non-obese male and female subjects were studied in a series of protocols, using a (13) C-acetate breath test… CONTINUE READING