Gastric anti-ulcer activity of leaf fractions obtained of polar extract from Wilbrandia ebracteata in mice

  title={Gastric anti-ulcer activity of leaf fractions obtained of polar extract from Wilbrandia ebracteata in mice},
  author={R. G. Coelho and F. G. Gonzalez and M. Sannomiya and L. C. Di Stasi and W. Vilegas},
  journal={Natural Product Research},
  pages={51 - 59}
  • R.G. Coelho, F. G. Gonzalez, +2 authors W. Vilegas
  • Published 2009
  • Medicine, Chemistry
  • Natural Product Research
  • Leaf fractions of Wilbrandia ebracteata were investigated for anti-ulcerogenic effects in ethanol and indomethacin-induced gastric ulcer assays in mice. Protective anti-ulcer effects were detected only in the ethanol-induced ulcer assay effects after pre-treatment with MeOH extract, MeOH chlorophyll-free, chlorophyll residue, HEX, DCM, aqueous MeOH fraction, ethyl acetate (EtOAc) and aqueous fractions. A potent anti-ulcerogenic effect was determined after pre-treatment of animals with EtOAc… CONTINUE READING
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