Gastric and lower esophageal sphincter pressures during nausea: a study using visual motion-induced nausea and high-resolution manometry.

@article{Schaub2014GastricAL,
  title={Gastric and lower esophageal sphincter pressures during nausea: a study using visual motion-induced nausea and high-resolution manometry.},
  author={Nora Schaub and Kee Peng Ng and Paul Kuo and Qasim Aziz and Daniel Sifrim},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2014},
  volume={306 9},
  pages={
          G741-7
        }
}
Nausea is the subjective unpleasant sensation that immediately precedes vomiting. Studies using barostats suggest that gastric fundus and lower esophageal sphincter (LES) relaxation precede vomiting. Unlike barostat, high-resolution manometry allows less invasive, detailed measurements of fundus pressure (FP) and axial movement of the gastroesophageal junction (GEJ). Nausea was induced in 12 healthy volunteers by a motion video and rated on a visual analog scale. FP was measured as the mean… CONTINUE READING

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