Gastric and duodenal HCO3- transport in vitro: effects of hormones and local transmitters.

@article{Flemstrm1982GastricAD,
  title={Gastric and duodenal HCO3- transport in vitro: effects of hormones and local transmitters.},
  author={Gunnar Flemstr{\"o}m and J. R. Heylings and Andrew Garner},
  journal={The American journal of physiology},
  year={1982},
  volume={242 2},
  pages={
          G100-10
        }
}
Luminal application of acid was recently shown to stimulate surface epithelial HCO3(-) transport in stomach and duodenum. Effects of some potential transmitters of this response were therefore studied in amphibian gastric fundic and proximal duodenal mucosa in vitro. Duodenal HCO3- transport, which could be titrated directly, was stimulated by dibutyryl cAMP (DBcAMP, 10(-6) M), the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (10(-6) M), noradrenaline (10(-6) M), pancreatic glucagon… CONTINUE READING

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