Gastric acid stimulating action of cysteamine in the rat.

  title={Gastric acid stimulating action of cysteamine in the rat.},
  author={Yasuko Ishii and Yoko Fujii and Masato Homma},
  journal={European journal of pharmacology},
  volume={36 2},
Cysteamine was previously found to produce duodenal ulcers in rats. In the present study, the effect of cysteamine on gastric secretion was studied. Cysteamine administered by a parenteral or intraduodenal route induced a marked and sustained increase in gastric secretion in conscious and in anesthetized rats. The response to cysteamine or its metabolite, cystamine, appeared gradually and the maximum response was observed in 2 or 3 hr after the administration. The response to cysteamine was… CONTINUE READING


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