Gastric Cytoprotective Activity of Ilicic Aldehyde in Rats and Mice

@article{Donadel2000GastricCA,
  title={Gastric Cytoprotective Activity of Ilicic Aldehyde in Rats and Mice},
  author={O. Donadel and A. Mar{\'i}a and G. Wendel and E. Guerreiro and O. Giordano},
  journal={Molecules},
  year={2000},
  volume={5},
  pages={462-464}
}
Ilicic alcohol, a natural sesquiterpene, was converted into an aldehyde by using Jones’ oxidation. The gastroprotective activity of ilicic aldehyde was evaluated in mice and rats. 

References

SHOWING 1-10 OF 10 REFERENCES
Structure−Cytoprotective Activity Relationship of Simple Molecules Containing an α,β-Unsaturated Carbonyl System
In previous reports we attributed the cytoprotective activity of several sesquiterpene lactones to the presence of a nonhindered electrophilic acceptor in their structure. We suggested that theExpand
Effect of OPC-12759, a novel antiulcer agent, on chronic and acute experimental gastric ulcer, and gastric secretion in rats.
TLDR
The results indicated that OPC-12759 possesses wide spectrum antiulcer activity as compared with cetraxate, and was effective at preventing the formation of acute gastric ulcers in various experimental ulcer models and on gastric secretion in rats. Expand
Cytoprotection by Prostaglandins in Rats Prevention of Gastric Necrosis Produced by Alcohol, HCl, NaOH, Hypertonic NaCl, and Thermal Injury
TLDR
It is suggested that certain prostaglandins, by a mechanism other than the inhibition of gastric acid secretion, maintain the cellular integrity of the gastric mucosa, and might be beneficial in the treatment of a variety of diseases in which Gastric mucosal injury is present. Expand
GASTROENTEROLOGY
Steatosis and steatohepatitis! • Aetiology alcohol, metabolic syndrome, starvation, Wilson’s, amiodarone, steroids! • NAFLD commonest liver disease in West; mostly related to metabolic syndrome! •Expand
J. Med. Chem
  • J. Med. Chem
  • 1997
Yabuuchi, Y. Japan J. Pharmacol
  • Yabuuchi, Y. Japan J. Pharmacol
  • 1989
Lab. of Theoretical and Physical Biology , U.S.A
  • Lab. of Theoretical and Physical Biology , U.S.A
  • 1988
Phytochemistry
  • Phytochemistry
  • 1979
«IV Simposio Internacional de Química de Productos Naturales y sus Aplicaciones»
  • «IV Simposio Internacional de Química de Productos Naturales y sus Aplicaciones»