Gastric Carcinogenesis by Duodenal Reflux Through Gut Regenerative Cell Lineage

  title={Gastric Carcinogenesis by Duodenal Reflux Through Gut Regenerative Cell Lineage},
  author={Ken-ichi Mukaisho and Koichi Miwa and Hitomi Kumagai and Masamichi Bamba and Hiroyuki Sugihara and Takanori Hattori},
  journal={Digestive Diseases and Sciences},
To elucidate the histogenesis of gastric stump cancer, we performed an operation in rats to make all duodenal contents flow back into the glandular stomach. The subjects were 41 rats, and sequential morphological changes of the duodenogastric stoma and the incidence of stump cancers were studied. Serial sections around the stoma were studied with mucin stains such as paradoxical concanavalin A (Con A), galactose oxidase Schiff (GOS), and high-iron diamine–Alcian blue (HID-AB). An… CONTINUE READING
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Muc gene expression in ulcerative colitis-related DALMs: a comparative immunohistochemistry study with colonic tumor

  • R Kushima, K Yamamoto, H Okabe, F Borchard, M Stolte, T Hattori
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