Gas-to-blood PCO2 differences during severe hypercapnia.

@article{Gurtner1979GastobloodPD,
  title={Gas-to-blood PCO2 differences during severe hypercapnia.},
  author={Gail H. Gurtner and Richard J. Traystman},
  journal={Journal of applied physiology: respiratory, environmental and exercise physiology},
  year={1979},
  volume={47 1},
  pages={
          67-71
        }
}
Five anesthetized dogs were made severely hypercapnic by stepwise addition of CO2 to their inspired air. Blood PCO2 levels greater than 400 Torr were reached. During hypercapnia, the steady-state end-tidal PCO2 (PaCO2) was always higher than the simultaneous measured arterial PCO2 (PaCO2). The mean ratio PaCO2/PACO2 was 0.861 +/- 0.01. These results are consistent with the predictions of the Charged Membrane Hypothesis, that gas-to-blood PCO2 differences should be directly proportional to the… CONTINUE READING

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