Gas mixing in the lungs of dogs and pigs.


We performed single breath washouts in 14 dogs and 4 pigs using a gas mixture containing 5% helium (He) and 5% sulphur hexafluoride (SF6) with, and without, an end inspiratory breathhold. In dogs, the slope of the alveolar plateau was steeper for SF6 than for He, the difference decreasing after 20 sec of breathholding. In contrast, in pigs there was no… (More)