Gas chromatography-mass spectrometry analysis of human mesenchymal stem cell metabolism during proliferation and osteogenic differentiation under different oxygen tensions.

Abstract

Bone marrow derived human mesenchymal stem cells (hMSC) are the primary cell type in bone tissue engineering, and their life span during osteogenic differentiation is associated with changes in oxygen tension. As a ubiquitous regulator of cellular metabolic activity, oxygen tension influences the profiles of metabolites in the entire metabolic network and… (More)
DOI: 10.1016/j.jbiotec.2013.11.010

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Cite this paper

@article{Muoz2014GasCS, title={Gas chromatography-mass spectrometry analysis of human mesenchymal stem cell metabolism during proliferation and osteogenic differentiation under different oxygen tensions.}, author={Nathalie Mu{\~n}oz and Junho Kim and Yijun Liu and Timothy M. Logan and Teng Ma}, journal={Journal of biotechnology}, year={2014}, volume={169}, pages={95-102} }