Gas chromatographic profiling and pattern recognition analysis of urinary organic acids from uterine myoma patients and cervical cancer patients.

@article{Kim1998GasCP,
  title={Gas chromatographic profiling and pattern recognition analysis of urinary organic acids from uterine myoma patients and cervical cancer patients.},
  author={K R Kim and Heung Gyu Park and Man Jeong Paik and Hyung Seok Ryu and Kyung Seung Oh and S W Myung and Hartmut M. Liebich},
  journal={Journal of chromatography. B, Biomedical sciences and applications},
  year={1998},
  volume={712 1-2},
  pages={11-22}
}
An efficient organic acid profiling and pattern recognition method is described for the correlation between urinary organic acid profiles and uterine cervical cancer. After methoximation of keto acids in alkalinized urine samples, all free organic acids were recovered by a dual solid-phase extraction procedure, followed by conversion to tert.-butyldimethylsilyl derivatives for the profiling analysis by dual-capillary column gas chromatography (GC) with subsequent screening for acids by… CONTINUE READING
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