Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability.

@article{Farhadi2003GasCM,
  title={Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability.},
  author={Ashkan Farhadi and Ali Keshavarzian and Earle W Holmes and Jeremy F Fields and Lei Zhang and Ali Banan},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2003},
  volume={784 1},
  pages={145-54}
}
We developed a capillary column gas chromatography (CCGC) method for the measurement of urinary sucralose (S) and three other sugar probes including, sucrose, lactulose (L) and mannitol (M) for use in in vivo studies of intestinal permeability. We compared the capillary method with a packed column gas chromatography (PCGC) method. We also investigated a possible role for sucralose as a probe for the measurement of whole gut permeability. Sample preparation was rapid and simple. The above four… CONTINUE READING
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