Gas chromatographic determination of pemoline in biological fluids using electron capture detection.

@article{Chu1977GasCD,
  title={Gas chromatographic determination of pemoline in biological fluids using electron capture detection.},
  author={S Y Chu and S T Sennello},
  journal={Journal of chromatography},
  year={1977},
  volume={137 2},
  pages={
          343-50
        }
}
10 Citations
Sensitive GLC assay for pemoline in biological fluids using nitrogen-specific detection.
  • D. Hoffman
  • Chemistry, Medicine
    Journal of pharmaceutical sciences
  • 1979
TLDR
Pemoline was extracted into methylene chloride as an ion-pair with tetrapentylammonium hydroxide under alkaline conditions and the N,N-dimethylpemoline derivative was yielded.
The use of the electron capture detector in human and equine doping analysis by gas chromatography
TLDR
Several examples of the confirmation of doping agents like amphetamines, ephedrine, phenylbutazone, pemoline and procaine by GC/ECD are given.
GC-MS identification of sympathomimetic amine drugs in urine: rapid methodology applicable for emergency clinical toxicology.
TLDR
A method was developed that permitted rapid identification in urine of the following sympathomimetic amines, suitable for clinical emergency toxicology purposes, and selected HFBA as the derivatizing agent of choice.

References

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Spectrophotometric determination of pemoline and mandelic acid in biological fluids.
TLDR
A rapid, simple spectrophotometric method which can be used to determine microgram quantities of pemoline and mandelic acid in biological fluids is described and should be capable of determining many other compoundsWhich can be converted to benzaldehyde.