Gas--liquid chromatographic determination of flurazepam and its major metabolites in plasma with electron-capture detection.

@article{Cooper1982GasliquidCD,
  title={Gas--liquid chromatographic determination of flurazepam and its major metabolites in plasma with electron-capture detection.},
  author={Syretha F. Cooper and D. Drolet},
  journal={Journal of chromatography},
  year={1982},
  volume={231 2},
  pages={321-31}
}
A sensitive and selective gas--liquid chromatographic method, using the electron-capture detector for the quantitative determination of flurazepam and its major blood metabolites is described. After extraction and back-extraction steps, flurazepam (I) is well separated from its main metabolites, N-1-hydroxyethylflurazepam (metabolite II) and N-1… CONTINUE READING