Garrod’s Croonian Lectures (1908) and the charter ‘Inborn Errors of Metabolism’: Albinism, alkaptonuria, cystinuria, and pentosuria at age 100 in 2008

@article{Scriver2008GarrodsCL,
  title={Garrod’s Croonian Lectures (1908) and the charter ‘Inborn Errors of Metabolism’: Albinism, alkaptonuria, cystinuria, and pentosuria at age 100 in 2008},
  author={Charles R. Scriver},
  journal={Journal of Inherited Metabolic Disease},
  year={2008},
  volume={31},
  pages={580-598}
}
Garrod presented his concept of ‘the inborn error of metabolism’ in the 1908 Croonian Lectures to the Royal College of Physicians (London); he used albinism, alkaptonuria, cystinuria and pentosuria to illustrate. His lectures are perceived today as landmarks in the history of biochemistry, genetics and medicine. Garrod gave evidence for the dynamic nature of metabolism by showing involvement of normal metabolites in normal pathways made variant by Mendelian inheritance. His concepts and… CONTINUE READING

7 Figures & Tables

Connections & Topics

Mentioned Connections BETA
Garrod presented his concept of ‘ the inborn error of metabolism’ in the 1908 Croonian Lectures to the Royal College of Physicians ( London ) ; he used albinism , alkaptonuria , cystinuria and pentosuria to illustrate .
Garrod ’s Croonian Lectures ( 1908 ) and the charter ‘ Inborn Errors of Metabolism’ : Albinism , alkaptonuria , cystinuria , and pentosuria at age 100 in 2008 .
Garrod ’s Croonian Lectures ( 1908 ) and the charter ‘ Inborn Errors of Metabolism’ : Albinism , alkaptonuria , cystinuria , and pentosuria at age 100 in 2008 .
Garrod presented his concept of ‘ the inborn error of metabolism’ in the 1908 Croonian Lectures to the Royal College of Physicians ( London ) ; he used albinism , alkaptonuria , cystinuria and pentosuria to illustrate .
All Topics