Garlic-induced alteration in rat liver and kidney morphology and associated changes in endogenous antioxidant status.

@article{Banerjee2001GarlicinducedAI,
  title={Garlic-induced alteration in rat liver and kidney morphology and associated changes in endogenous antioxidant status.},
  author={Sanjay Kumar Banerjee and Mohua Maulik and Subhash Chandra Manchanda and Amit Kumar Dinda and Tushar Kanti Das and Subir Kumar Maulik},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2001},
  volume={39 8},
  pages={793-7}
}
The effects of chronic garlic intake on various endogenous antioxidant enzymes and lipid peroxidation on two major organs, the liver (L) and kidneys (K), were investigated. Wistar albino rats were fed with fresh garlic homogenate daily by gavage in three different doses (250, 500 and 1000 mg/kg/day) for 30 days. After this period, rats were sacrificed and liver and kidneys were harvested for biochemical estimation. In comparison to saline-treated rats, the 250 mg/kg/day dose significantly (P<0… CONTINUE READING