Garlic extract ameliorates renal and cardiopulmonary injury in the rats with chronic renal failure.

@article{Deniz2011GarlicEA,
  title={Garlic extract ameliorates renal and cardiopulmonary injury in the rats with chronic renal failure.},
  author={M Levent Deniz and G{\"o}ksel Şener and Fer{\'i}ha Ercan and Berrak Cağlayan Yeğen},
  journal={Renal failure},
  year={2011},
  volume={33 7},
  pages={718-25}
}
Chronic renal failure (CRF) is associated with oxidative stress that promotes production of reactive oxygen species and cytokine release. We aimed to investigate the possible protective and antioxidant effects of aqueous garlic extract (AGE) in a rat model of CRF. Male Sprague-Dawley rats were randomly assigned as either CRF group with 5/6 reduction in the renal mass or sham-operated control group. CRF group received either saline or AGE (250 mg/kg/day/1 mL) orally for 3 weeks. At the end of… CONTINUE READING
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