Garlic and aging: new insights into an old remedy
@article{Rahman2003GarlicAA,
title={Garlic and aging: new insights into an old remedy},
author={Khalid Rahman},
journal={Ageing Research Reviews},
year={2003},
volume={2},
pages={39-56}
}There has been an impressive gain in individual life expectancy with parallel increases in age-related chronic diseases of the cardiovascular, brain and immune systems. These can cause loss of autonomy, dependence and high social costs for individuals and society. It is now accepted that aging and age-related diseases are in part caused by free radical reactions. The arrest of aging and stimulation of rejuvenation of the human body is also being sought. Over the last 20 years the use of herbs… Expand
233 Citations
Garlic and Aging: Current Knowledge and Future Considerations
- Medicine
- 2010
Scientific and clinical studies have shown that garlic can enhance immunity, protect against infection and inflammation, and help lower the risk of cancer, heart disease, and dementia, the most common form of which is Alzheimer’s disease. Expand
Neuroprotective Effects of Garlic A Review
- Medicine
- The Libyan journal of medicine
- 2008
The broad range of anti-atherogenic, antioxidant and anti-apoptotic protection afforded by garlic may be extended to its neuroprotective action, helping to reduce the risk of dementia, including vascular dementia and AD. Expand
Neuroprotective effects of garlic a review.
- Medicine
- 2008
The broad range of anti-atherogenic, antioxidant and anti-apoptotic protection afforded by garlic may be extended to its neuroprotective action, helping to reduce the risk of dementia, including vascular dementia and AD. Expand
Garlic and Heart Health
- Medicine
- 2010
Evidence supports the fact that regular consumption of garlic can reducing factors associated with cardiovascular disease and suggests that garlic can reduce serum lipids in hypercholesterolemic subjects and has strong antioxidant properties and can reduce oxidative stress by increasing the availability of nitric oxide. Expand
Studies on free radicals, antioxidants, and co-factors
- Medicine
- Clinical interventions in aging
- 2007
The aim of this review is to highlight the main themes from studies on free radicals, antioxidants and co-factors, and to propose an evidence-based strategy for healthy aging. Expand
Significance of Garlic and Its Constituents in Cancer and Cardiovascular Disease Garlic and Cardiovascular Disease : A Critical Review 1 , 2
- 2006
Epidemiologic studies show an inverse correlation between garlic consumption and progression of cardiovascular disease. Cardiovascular disease is associated with multiple factors such as raised serum… Expand
Effects of Allium sativum in cardiovascular diseases: A Review
- Medicine
- 2014
It is concluded that although garlic appears to hold promise in reducing parameters associated with cardiovascular disease, more in-depth and appropriate studies are required. Expand
Significance of Garlic and Its Constituents in Cancer and Cardiovascular Disease Antiglycation Properties of Aged Garlic Extract : Possible Role in Prevention of Diabetic Complications 1 , 2
- 2006
Diabetes mellitus is a common endocrine disorder characterized by hyperglycemia and long-term complications affecting the eyes, nerves, blood vessels, skin, and kidneys. Increased glycation of… Expand
Garlic and cardiovascular disease: a critical review.
- Medicine
- The Journal of nutrition
- 2006
It is concluded that although garlic appears to hold promise in reducing parameters associated with cardiovascular disease, more in-depth and appropriate studies are required. Expand
Antiglycation properties of aged garlic extract: possible role in prevention of diabetic complications.
- Medicine
- The Journal of nutrition
- 2006
Aged garlic extract and S-allylcysteine deserve more attention and should be investigated to see whether they can reduce AGEPs in vivo. Expand
References
SHOWING 1-10 OF 113 REFERENCES
A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects.
- Medicine
- Free radical biology & medicine
- 2001
It is extremely important to explore methods to retard or reverse age-related neuronal deficits as well as their subsequent, behavioral manifestations, and a new role in which certain dietary components are beginning to receive increased attention, in particular those involving phytochemicals found in fruits and vegetables. Expand
Historical perspective on garlic and cardiovascular disease.
- Medicine
- The Journal of nutrition
- 2001
Evidence obtained indicates that garlic has potential in the prevention and control of cardiovascular disorders and is beneficial when taken as a dietary supplement. Expand
Free radical theory of aging.
- Chemistry, Medicine
- Mutation research
- 1992
The free radical theory of aging postulates that aging changes are caused by free radical reactions, and data indicate that average life expectancy at birth may be increased by 5 or more years, by nutritious low caloric diets supplemented with one or more free radical reaction inhibitors. Expand
Ageing Research Reviews
- Medicine
- 2004
Ageing Research Reviews (ARR) covers the trends in this field of ageing research, with an emphasis on cellular and molecular mechanisms of the ageing process and age-related diseases such as cancer, cardiovascular disease, diabetes and neurodegenerative disorders. Expand
Clinical relevance of age-related immune dysfunction.
- Medicine
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2000
This perspective will review clinically relevant infections in the elderly, focusing on influenza and influenza virus vaccination and how chronic illness contributes to increased risk and severity of infection and/or failed vaccine response. Expand
Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions.
- Medicine
- The Journal of nutrition
- 2001
Aged garlic extract exerts selective inhibition on platelet aggregation and adhesion, platelet functions that may be important for the development of cardiovascular events such as myocardial infarction and ischemic stroke. Expand
Aging of the vascular-wall and atherosclerosis
- Medicine
- Experimental Gerontology
- 1999
Although hyperlipidemia appears to be involved both in plaque formation and wall thickness progression, the detailed mechanisms are not identical and in the oldest age group (above 80 years and in centenarians), high cholesterol values may not be a risk factor as in younger individuals. Expand
Nutritional Factors in Cerebral Aging and Dementia: Epidemiological Arguments for a Role of Oxidative Stress
- Medicine
- Neuroepidemiology
- 2001
A progress report on the more recent results of the various epidemiologic cohorts studied for the association between nutrition of older people, the evolution of cognitive performances and the risk of later occurrence of dementia or stroke is given. Expand
Testing garlic for possible anti-ageing effects on long-term growth characteristics, morphology and macromolecular synthesis of human fibroblasts in culture.
- Biology, Medicine
- Journal of ethnopharmacology
- 1994
The results show that an addition of garlic extract into the normal cell culture medium can support serial subculturing for over more than 55 population doublings in 475 days, and that this treatment has some youth-preserving, anti-ageing and beneficial effects on human fibroblasts in terms of maximum proliferative capacity and morphological characteristics. Expand
The impact of antioxidants on chronic disease in ageing and in old age.
- Medicine
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
- 1999
It should be possible to resolve in the near future the question whether two days' RDA's are still adequate or whether the intake should be revised upwards and the highly interactive antioxidative system in the body strongly suggests that a well-balanced adequate intake of different antioxidants will be superior in its protective action to the supplementation with one single compound. Expand