Garlic Attenuates Cardiac Oxidative Stress via Activation of PI3K/AKT/Nrf2-Keap1 Pathway in Fructose-Fed Diabetic Rat

@inproceedings{Padiya2014GarlicAC,
  title={Garlic Attenuates Cardiac Oxidative Stress via Activation of PI3K/AKT/Nrf2-Keap1 Pathway in Fructose-Fed Diabetic Rat},
  author={Raju Padiya and Debabrata Paul Chowdhury and Roshan M. Borkar and Ragampeta Srinivas and Manika Pal Bhadra and Sanjay Kumar Banerjee},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Cardiovascular complication due to diabetes has remained a major cause of death. There is an urgent need to intervene the cardiac complications in diabetes by nutritional or pharmacological agents. Thus the present study was designed to find out the effectiveness of garlic on cardiac complications in insulin-resistant diabetic rats. METHODS AND RESULTS SD rats were fed high fructose (65%) diet alone or along with raw garlic homogenate (250 mg/kg/day) or nutrient-matched (65% corn… CONTINUE READING

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