Garcinia mangostana Linn displays antidepressant-like and pro-cognitive effects in a genetic animal model of depression: a bio-behavioral study in the Flinders Sensitive Line rat

@article{Oberholzer2017GarciniaML,
  title={Garcinia mangostana Linn displays antidepressant-like and pro-cognitive effects in a genetic animal model of depression: a bio-behavioral study in the Flinders Sensitive Line rat},
  author={Inge Oberholzer and Marisa M{\"o}ller and Brendan John Holland and Olivia M Dean and Michael Berk and Brian Herbert Harvey},
  journal={Metabolic Brain Disease},
  year={2017},
  pages={1-14}
}
There is abundant evidence for both disorganized redox balance and cognitive deficits in major depressive disorder (MDD). Garcinia mangostana Linn (GM) has anti-oxidant activity. We studied the antidepressant-like and pro-cognitive effects of raw GM rind in Flinders Sensitive Line (FSL) rats, a genetic model of depression, following acute and chronic treatment compared to a reference antidepressant, imipramine (IMI). The chemical composition of the GM extract was analysed for levels of α- and… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 7 times. VIEW TWEETS

References

Publications referenced by this paper.
SHOWING 1-10 OF 93 REFERENCES

Similar Papers

Loading similar papers…