GapFiller: a de novo assembly approach to fill the gap within paired reads

@inproceedings{Nadalin2012GapFillerAD,
  title={GapFiller: a de novo assembly approach to fill the gap within paired reads},
  author={Francesca Nadalin and Francesco Vezzi and Alberto Policriti},
  booktitle={BMC Bioinformatics},
  year={2012}
}
Next Generation Sequencing technologies are able to provide high genome coverages at a relatively low cost. However, due to limited reads' length (from 30 bp up to 200 bp), specific bioinformatics problems have become even more difficult to solve. De novo assembly with short reads, for example, is more complicated at least for two reasons: first, the… CONTINUE READING
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