Gap junctions modulate seizures in a mean-field model of general anesthesia for the cortex

@article{SteynRoss2012GapJM,
  title={Gap junctions modulate seizures in a mean-field model of general anesthesia for the cortex},
  author={Moira L. Steyn-Ross and D. Alistair Steyn-Ross and Jamie W. Sleigh},
  journal={Cognitive Neurodynamics},
  year={2012},
  volume={6},
  pages={215-225}
}
During slow-wave sleep, general anesthesia, and generalized seizures, there is an absence of consciousness. These states are characterized by low-frequency large-amplitude traveling waves in scalp electroencephalogram. Therefore the oscillatory state might be an indication of failure to form coherent neuronal assemblies necessary for consciousness. A generalized seizure event is a pathological brain state that is the clearest manifestation of waves of synchronized neuronal activity. Since gap… CONTINUE READING
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