Gap junctions mediate intercellular calcium signalling in cultured articular chondrocytes.

@article{Dandrea1996GapJM,
  title={Gap junctions mediate intercellular calcium signalling in cultured articular chondrocytes.},
  author={Paola D'andrea and Franco Vittur},
  journal={Cell calcium},
  year={1996},
  volume={20 5},
  pages={389-97}
}
Gap junction-mediated intercellular communication has been implicated in a variety of cellular functions. Among these, signal transduction can be coordinated among several cells due to gap junctional permeability to intracellular second messengers. Chondrocytes from articular cartilage in primary culture respond to extracellular ATP by rhythmically increasing their cytosolic Ca2+ concentration. Digital imaging fluorescence microscopy of Fura-2 loaded cells was used to monitor Ca2+ in confluent… CONTINUE READING
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