Gap junctions in Drosophila: developmental expression of the entire innexin gene family

@article{Stebbings2002GapJI,
  title={Gap junctions in Drosophila: developmental expression of the entire innexin gene family},
  author={Lucy A. Stebbings and Martin G. Todman and Rose J Phillips and Claire E Greer and Jennifer Tam and Pauline Phelan and Kirsten Jacobs and Jonathan P. Bacon and Jane A. Davies},
  journal={Mechanisms of Development},
  year={2002},
  volume={113},
  pages={197-205}
}
Invertebrate gap junctions are composed of proteins called innexins and eight innexin encoding loci have been identified in the now complete genome sequence of Drosophila melanogaster. The intercellular channels formed by these proteins are multimeric and previous studies have shown that, in a heterologous expression system, homo- and hetero-oligomeric channels can form, each combination possessing different gating characteristics. Here we demonstrate that the innexins exhibit complex… CONTINUE READING
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Innexins in the developing central nervous system of Drosophila

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9 Excerpts

2002s. Two Drosophila innexins form rectifying heterotypic gap junctions with complex voltage gating characteristics

  • M. G. Todman, K. Jacobs, L. A. Stebbings, J. P. Bacon, J. A. Davies
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Gap junction communication in invertebrates : the innexin gene family

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