Gap junctions between striatal fast-spiking interneurons regulate spiking activity and synchronization as a function of cortical activity.

@article{Hjorth2009GapJB,
  title={Gap junctions between striatal fast-spiking interneurons regulate spiking activity and synchronization as a function of cortical activity.},
  author={Johannes Hjorth and Kim T. Blackwell and Jeanette Kotaleski},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2009},
  volume={29 16},
  pages={5276-86}
}
Striatal fast-spiking (FS) interneurons are interconnected by gap junctions into sparsely connected networks. As demonstrated for cortical FS interneurons, these gap junctions in the striatum may cause synchronized spiking, which would increase the influence that FS neurons have on spiking by the striatal medium spiny (MS) neurons. Dysfunction of the basal ganglia is characterized by changes in synchrony or periodicity, thus gap junctions between FS interneurons may modulate synchrony and… CONTINUE READING

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