• Biology, Medicine
• Published in Endocrinology 2011
• DOI:10.1210/en.2010-1311

Gap junctions between neuronal inputs but not gonadotropin-releasing hormone neurons control estrous cycles in the mouse.

@article{Campbell2011GapJB,
  title={Gap junctions between neuronal inputs but not gonadotropin-releasing hormone neurons control estrous cycles in the mouse.},
  author={Rebecca E Campbell and Eric Ducret and Robert K. Porteous and Xinhuai Liu and Michel K. Herde and Kerstin Wellerhaus and Stephan Sonntag and Klaus Willecke and Allan E Herbison},
  journal={Endocrinology},
  year={2011},
  volume={152 6},
  pages={
          2290-301
        }
}

• Rebecca E Campbell, Eric Ducret, +6 authors Allan E Herbison

The role of gap junctions in the neural control of fertility remains poorly understood. Using acute brain slices from adult GnRH-green fluorescent protein transgenic mice, individual GnRH neurons were filled with a mixture of fluorescent dextran and neurobiotin. No dye transfer was found between any GnRH neurons, although approximately 30% of GnRH neurons exchanged neurobiotin with closely apposed cells. Dual electrophysiological recordings from pairs of GnRH neurons revealed an absence of… CONTINUE READING

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