Gap junctions, homeostasis, and injury.

  title={Gap junctions, homeostasis, and injury.},
  author={Antonio De Maio and Virginia Loreto Vega and Jorge E Contreras},
  journal={Journal of cellular physiology},
  volume={191 3},
Gap junctions (Gj) play an important role in the communication between cells of many tissues. They are composed of channels that permit the passage of ions and low molecular weight metabolites between adjacent cells, without exposure to the extracellular environment. These pathways are formed by the interaction between two hemichannels on the surface of opposing cells. These hemichannels are formed by the association of six identical subunits, named connexins (Cx), which are integral membrane… CONTINUE READING

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