Gantrez AN as a new polymer for the preparation of ligand-nanoparticle conjugates.

@article{Arbs2002GantrezAA,
  title={Gantrez AN as a new polymer for the preparation of ligand-nanoparticle conjugates.},
  author={Pau Arb{\'o}s and M. Ruzhansky-J. Wirth and Miguel Angel Arangoa and Franz Gabor and Juan M Irache},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2002},
  volume={83 3},
  pages={321-30}
}
The aim of this study was to evaluate the feasibility and in vitro activity of ligand-conjugates based on the use of poly(methyl vinyl ether-co-maleic anhydride) (PVM/MA or Gantrez AN). Fluorescently labelled PVM/MA nanoparticles were prepared by desolvation and cross-linkage with 1,3-diaminopropane (DP). Conjugates were obtained by incubation between the carriers and Sambucus nigra agglutinin (SNA) for 1 h in an aqueous medium. The lectin binding to the surface of nanoparticles was increased… CONTINUE READING