Gangliosides as a Double-Edged Sword in Neurodegenerative Disease


Gangliosides are sialic acid-containing glycolipids that are mainly localized in the outer leaflet of the plasma membrane of vertebrate cells and are involved in diverse physiological functions such as cell growth, differentiation, and cell-cell recognition(Hakomori, 1990). In the nervous system, gangliosides are highly expressed in neurons and are… (More)


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@inproceedings{Sekigawa2012GangliosidesAA, title={Gangliosides as a Double-Edged Sword in Neurodegenerative Disease}, author={Akio Sekigawa and Masayo Fujita and Kazunari Sekiyama and Yoshiki Takamatsu and Jianshe Wei and Makoto Hashimoto}, year={2012} }