Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors

Abstract

BACKGROUND Oxaliplatin, an effective antineoplastic agent againstgastrointestinal tumors, can cause severe peripheral neurotoxicity, which seriously limits its clinical application. To date, there are no effective treatments for this complication. Ganglioside-monosialic acid (GM1) has been shown to protect neurons against injuries and degeneration. The aim… (More)
DOI: 10.1186/1477-7819-11-19

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Cite this paper

@inproceedings{Zhu2013GangliosidemonosialicA, title={Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors}, author={Yanyun Zhu and Junlan Yang and Shunchang Jiao and Tiefeng Ji}, booktitle={World journal of surgical oncology}, year={2013} }